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武汉艾美捷科技有限公司

产品介绍

艾美捷Ansamitocin P3安丝菌素P3解决方案

价 格:¥电议

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发布日期:2023/5/31 17:09:05

更新日期:2023/5/31 17:09:05

详细内容

 Ansamitocin P3通过结合微管蛋白诱导微管解聚;它具有免疫调节和抗癌活性。安萨霉素P3增加T细胞信号传导和抗原摄取,并降低体内调节性T细胞水平。

 

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艾美捷Ansamitocin P3 #LKT-A5472-5mg相关信息:

cas#66547-09-9

纯度:≥70%

公式:C32H43CIN2O9

配方重量:635.14

溶解度:10毫米二甲基二甲基苯甲酸

储存温度:-20°C

 

Description

Ansamitocin P3 induces microtubule depolymerization by binding tubulin; it exhibits immunomodulatory and anticancer activities. Ansamitocin P3 increases T cell signaling and antigen uptake and decreases regulatory T cell levels in vivo.

 

Product Info

Cas No. 66547-09-9

Purity 70%

Formula C32H43CIN2O9

Formula Wt. 635.14

Solubility 10mM DMSO

 

Ansamitocin P3文献参考:

Martin K, Müller P, Schreiner J, et al. The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity. Cancer Immunol Immunother. 2014 Sep;63(9):925-38. PMID: 24906866.

 

Venghateri JB, Gupta TK, Verma PJ, et al. Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at the vinblastine site. PLoS One. 2013 Oct 4;8(10):e75182. PMID: 24124473.

 

来源:https://www.amyjet.com/products/LKT-A5458-1mg.shtml

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