产品介绍
艾美捷Ansamitocin P3安丝菌素P3解决方案
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发布日期:2023/5/31 17:09:05
更新日期:2023/5/31 17:09:05
详细内容
艾美捷Ansamitocin P3 #LKT-A5472-5mg相关信息:
cas#:66547-09-9
纯度:≥70%
公式:C32H43CIN2O9
配方重量:635.14
溶解度:10毫米二甲基二甲基苯甲酸
储存温度:-20°C
Description
Ansamitocin P3 induces microtubule depolymerization by binding tubulin; it exhibits immunomodulatory and anticancer activities. Ansamitocin P3 increases T cell signaling and antigen uptake and decreases regulatory T cell levels in vivo.
Product Info
Cas No. 66547-09-9
Purity ≥70%
Formula C32H43CIN2O9
Formula Wt. 635.14
Solubility 10mM DMSO
Ansamitocin P3文献参考:
Martin K, Müller P, Schreiner J, et al. The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity. Cancer Immunol Immunother. 2014 Sep;63(9):925-38. PMID: 24906866.
Venghateri JB, Gupta TK, Verma PJ, et al. Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at the vinblastine site. PLoS One. 2013 Oct 4;8(10):e75182. PMID: 24124473.