产品介绍
Abcam抗体CD11b antibody [EP1345Y] ab52478
价 格:¥电议
型 号:ab52478
产品完善度:
生产地:其他访问量:140次
发布日期:2011/10/6 18:17:47
更新日期:2012/1/11 9:39:14
详细内容
Abcam抗体CD11b antibody [EP1345Y] ab52478
Product Name | CD11b antibody [EP1345Y] |
Product type | Primary antibodies |
Description | Rabbit monoclonal [EP1345Y] to CD11b |
Immunogen | Synthetic peptide corresponding to C terminus of human CD11b |
Reacts with | Hu |
Does not react with | Ms, Rat |
Specificity | This antibody reacts with CD11b |
Tested applications | Flow Cyt, ICC, IHC-P, IP, WB |
Abreviews
|
| ||||||
Application notes | Recommended dilutions | ||||||
Positive control | IHC-P: Human spleen tissue | ||||||
Research areas | Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Neutrophil Lineage | ||||||
Target | |||||||
Function | Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. | ||||||
Tissue specificity | Predominantly expressed in monocytes and granulocytes. |