产品介绍
Recombinant Human GM-CSF Peprotech进口原装
价 格：￥电议
型 号：300-03
产品完善度：
生产地：其他访问量：32次
发布日期：2016/1/26 9:11:45
更新日期：2016/1/26 9:11:45
详细内容
Recombinant Human GM-CSF Peprotech进口原装
产品编号:
300-03
别名:
Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α
描述:
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils ａnd macrophages, ａnd promotes the proliferation ａnd development of early erythroid megakaryocytic ａnd eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts ａnd T-lymphocytes. GM-CSF inhibits neutrophil migration ａnd enhances the functional activity of the mature end-cells. The human ａnd murine molecules are species-specific ａnd exhibit no cross-species reactivity. Recombinant Human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids, containing two intramolecular disulfide bonds ａnd two potential N-linked glycosylation sites.
氨基酸序列:
MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
交叉反应:
Human, Bacteria, Mouse, Leech, Pig, Human + Mouse
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
