PSMB8 [H2-A5] Catalog Number：OM627709_产品说明_ B2B电子商务综合技术文献

发布时间：2024/9/27点击次数：8

Product Name	PSMB8 [H2-A5]
Antibody Type	Primary Antibodies
Product description	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. Proteasomes are distributed throughout eukaryotic cells at a high concentration ａnd cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. More
Immunogen	Recombinant protein

Alternative Names	ALDD antibody D6S216 antibody D6S216E antibodyLarge multifunctional peptidase 7 antibody Large multifunctional protease 7 antibody LMP 7 antibody LMP7 antibody Low molecular mass protein 7 antibody Low molecular weight protein 7 antibody Macropain subunit C13 antibody MGC1491 antibody Multicatalytic endopeptidase complex subunit C13 antibody NKJO antibody OTTHUMP00000062981 antibody Protease component C13 antibody Proteasome (prosome macropain) subunit beta type 8 antibody Proteasome (prosome macropain) subunit beta type 8 (large multifunctional peptidase 7) antibody Proteasome beta 8 subunit antibody Proteasome catalytic subunit 3i antibody Proteasome component C13 antibody Proteasome related gene 7 antibody Proteasome subunit beta 5i antibody Proteasome subunit beta 8 antibody Proteasome subunit beta type 8 antibody Proteasome subunit beta type antibody Proteasome subunit beta type-8 antibody Proteasome subunit beta-5i antibody Proteasome subunit Y2 antibody PSB8_HUMAN antibody PSMB 8 antibody PSMB5i antibody PSMB8 antibody Really interesting new gene 10 protein antibody RING 10 antibody RING10 antibody Y2 antibody More
Molecular Weight(MW)	22 kDa
Cellular Localization	Cylasm. Nucleus.

SwissProt ID	P28062 P28064

Application

Fig1: Western blot analysis of PSMB8 on human PSMB8 recombinant protein using anti-PSMB8 antibody at 1/1,000 dilution.
Application

Fig2: Western blot analysis of PSMB8 on different cell lysates using anti-PSMB8 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: MCF-7 Lane 3: A431 Lane 4: RAJI Lane 5: MOTL4 Lane 6: PC-12
Application

Fig3: ICC staining PSMB8 (green) ａnd actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application

Fig4: Immunohistochemical analysis of paraffin-embedded intima cancer tissue using anti-PSMB8 antibody. Counter stained with hematoxylin.
Application

Fig5: Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-PSMB8 antibody. Counter stained with hematoxylin.

Application Notes	WB:1:500-1:2,000 ICC:1:100-1:500 IHC:1:100-1:500

Form	Liquid
Storage Instructions	Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer	1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.

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