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DLGAP1 antibody Catalog Number:OM250145

发布时间:2024/9/29点击次数:37

 

Product Profile

Product Name DLGAP1 antibody
Antibody Type Primary Antibodies
Product description
Rabbit polyclonal antibody to DLGAP1SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM). At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins.
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Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAICC/IFIHC-PWB

 
ICC/IF:1:200~1:500
IHC-P:1:50~1:200
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
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Species Reactivity

Human

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
Disks largeassociated protein1
DAP1
DAP-1
Disks large-associated protein 1
SAP90/PSD-95-associated protein 1
Disks largeassociated protein 1
SAPAP1
SAP90/PSD95associated protein 1
GKAP
SAP90/PSD95associated protein1
DLGAP1
DAP 1
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Target DLGAP1
Tissue Specificity This antibody is specific for DLGAP1

Application

  • Application

    Immunohistochemistry of SAPAP1 in human brain with SAPAP1 antibody at 5 ug/ml.

  • Application

    Immunofluorescence of SAPAP1 in Human Brain cells with SAPAP1 antibody at 20 ug/mL.

  • Application

    Western blot analysis of SAPAP1 in human brain tissue lysate with SAPAP1 antibody at (A) 0.5 and (B) 1 ug/ml.

Positive Control Blocking Peptide:
Application Notes
ICC/IF:1:200~1:500
IHC-P:1:50~1:200
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
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Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer PBS containing 0.02% sodium azide
 

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