SUMO2/3 Antibody (C-term E69) Catalog Number：OM222317_产品说明_ B2B电子商务综合技术文献

发布时间：2024/9/30点击次数：29

Product Name	SUMO2/3 Antibody (C-term E69)
Antibody Type	Primary Antibodies

Gene Synonyms	SMT3B SMT3H1
Alternative Names	SUMO3 SMT3B SMT3H1 Small ubiquitin-related modifier 3 SMT3 homolog 1 SUMO-2 Ubiquitin-like protein SMT3B More
Molecular Weight(MW)	11637 Da
Function	Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation ａnd may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication ａnd repair, mitosis ａnd signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 ａnd linkage to the E2 enzyme UBE2I, ａnd can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4 More
Tissue Specificity	Expressed predominantly in liver.
Cellular Localization	Cylasm.

Entrez Gene	6612

Application

Western blot analysis of anti-SUMO2/3 Antibody (C-term E69) in CEM cell line lysates (35ug/lane).SUMO2/3(arrow) was detected using the purified Pab.
Application

Formalin-fixed ａnd paraffin-embedded human hepatocarcinoma tissue reacted with SUMO2/3 antibody (C-term E69) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application

Western blot analysis of SUMO2/3 (arrow) using rabbit polyclonal SUMO2/3 Antibody (C-term E69) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SUMO2/3 gene.

Application Notes	WB~~1:50~100 IHC~~1:10~50:

Form	Liquid
Storage Instructions	For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

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