Fibrinogen gamma antibody Catalog Number：OM253133_产品说明_ B2B电子商务综合技术文献

发布时间：2024/9/19点击次数：7

Product Name	Fibrinogen gamma antibody
Antibody Type	Primary Antibodies
Product description	Rabbit polyclonal antibody to Fibrinogen gamma (fibrinogen gamma chain)The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq] More
Immunogen	Recombinant protein encompassing a sequence within the center region of human Fibrinogen gamma. The exact sequence is proprietary.

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	ICC/IFIHC-PWB
	*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity	HumanMouse
Predicted Reactivity	Rat, Pig, Chicken, BovineRat (91%), Pig (88%), Chicken (81%), Bovine (88%)
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration)
Purification	Affinity purified

Gene Synonyms	FGG antibody "fibrinogen gamma polypeptide antibody" fibrinogen gamma chain antibody More
Target	Fibrinogen gamma
Molecular Weight(MW)	52 kDa (note) (3)
Cellular Localization	Secreted

Application

Fibrinogen gamma antibody detects Fibrinogen gamma protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, ａnd the membrane was blotted with Fibrinogen gamma antibody diluted by 1:1000.
Application

Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Fibrinogen gamma antibody at 1:200 dilution.
Application

Fibrinogen gamma antibody detects Fibrinogen gamma protein by western blot analysis. Human plasma ａnd HepG2 conditioned medium were separated by 10% SDS-PAGE, ａnd the membrane was blotted with Fibrinogen gamma antibody diluted at 1:2000.
Application

Fibrinogen gamma antibody detects Fibrinogen gamma protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: Fibrinogen gamma antibody dilution: 1:250.
Application

Fibrinogen gamma antibody detects Fibrinogen gamma protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 10% SDS-PAGE, ａnd the membrane was blotted with Fibrinogen gamma antibody diluted at 1:1000.

Positive Control	293T , A431 , HeLa , HepG2 , human plasma , HepG2 sup. , Mouse plasma
Application Notes	*Optimal dilutions/concentrations should be determined by the researcher. :

Form	Liquid
Storage Instructions	Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

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